Methods for treating diseases using isoindoline compounds

Patent Number: 9387195

Patent Date: 2016-07-12

Patent type: utility

Methods of treating a disease selected from dermatomyositis, prurigo nodularis, pyoderma gangrenosum, alopecia areata, hidradenitis suppurtiva, rosacea, lichen planus, giant cell arteritis, Sjogren's syndrome, gout, chronic prostatitis, posterior uveitis, vulvodynia and interstitial cystitis in a human are disclosed. Specific methods encompass the administration of (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, cyclopropyl {2-[(15)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-3-oxoisoindolin-4-yl}carboxamide or a combination thereof, or a pharmaceutically acceptable prodrug, metabolite, polymorph, salt, solvate or clathrate thereof.

Inventors

First Name Last Name City State Country
Peter H. Schafer - - -
Sai L. Shankar - - -

IPCs

Section Class Sub Class Group Sub Group
A 61 K 31 4035
A 61 K 9 00
A 61 K 9 20
A 61 K 31 5575
A 61 K 45 06
A 61 K 47 38
A 61 K 47 06
A 61 K 47 10
A 61 K 47 14
A 61 K 47 26
A 61 K 9 06
A 61 K 9 48
A 61 K 9 70

Assignee

Organization First Name Last Name City State Country
Celgene Corporation - - - - -