Methods and compositions for the inhibition of fructokinase

Patent Number: 9387245

Patent Date: 2016-07-12

Patent type: utility

The invention relates to the use of isoform-specific fructokinase (ketohexokinase) (KHK) inhibitors alone or in combination with various agents to both prevent and treat a wide variety of diseases including, but not limited to, sugar craving, obesity, features of metabolic syndrome (including insulin resistance, hypertriglyceridemia, hypertension, and fatty liver), polyuria, proximal tubular injury, and diabetic kidney disease.

Inventors

First Name	Last Name	City	State	Country
Richard J.	Johnson	-	-	-
Miguel A.	Lanaspa-Garcia	-	-	-
Takuji	Ishimoto	-	-	-

IPCs

Section	Class	Sub Class	Group	Sub Group
A	61	K	45	06
A	61	K	38	00
C	12	N	15	113
A	61	K	39	395
C	07	K	16	40
A	61	K	31	415
A	61	K	31	7052
A	61	K	31	427
C	12	N	9	12
A	61	K	31	425

Assignee

Organization	First Name	Last Name	City	State	Country
The University of Colorado, a body corporate	-	-	-	-	-