DIAGNOSTIC IMAGING

Brand	Owner	Address	Description
NPATH	Putman, Matthew C.	2251 FRONT STREET, SUITE 110 CUYAHOGA FALLS OH 44223	diagnostic imaging, analysis and control software for imaging apparatus for medical and biological applications;N PATH; NANOTRONICS PATH;
	Where the owner name is not linked, that owner no longer owns the brand

Technical Examples

Cyanine dye bioconjugates useful for diagnostic imaging and therapy are disclosed. The conjugates include several cyanine dyes with a variety of bis- and tetrakis (carboxylic acid) homologs. The compounds may be conjugated to bioactive peptides, carbohydrates, hormones, drugs, or other bioactive agents. The small size of the compounds allows more favorable delivery to tumor cells as compared to larger molecular weight imaging agents. The various dyes are useful over the range of 350 to 1300 nm, the exact range being dependent upon the particular dye. The use of dimethylsulfoxide helps to maintain the fluorescence of the compounds. The inventive compounds are useful for diagnostic imaging and therapy, in endoscopic applications for the detection of tumors and other abnormalities, for localized therapy, for photoacoustic tumor imaging, detection and therapy, and for sonofluoresence tumor imaging, detection and therapy.