BIOMARKER PREPARATIONS CO ADMINISTRATION WITH

Brand	Owner	Address	Description
ADHEREMARK	SYNAPSE BIOSCIENCES	4114 NC Hwy 57 Hillsborough NC 27278	biomarker preparations for co-administration with pharmaceuticals, for diagnostic determination of medication compliance; pharmaceutical preparations comprising biomarker ingredients, for diagnostic determination of medication compliance; specialized tablets, capsules and powders for the delivery of pharmaceuticals sold without the pharmaceutical ingredient; drug delivery agents consisting of compounds that provide diagnostic verification of medication compliance;diagnostic medical services, namely, testing of physiological samples for medication compliance; preparation of diagnostic medication compliance reports for individuals subject to medication administration schedules; monitoring services, namely, diagnostic testing of physiological samples of individuals engaged in pharmaceutical clinical trials conducted by others, and assessment and reporting of medication compliance of such individuals;
	Where the owner name is not linked, that owner no longer owns the brand

Technical Examples

Methods and compositions for identifying high-grade cervical disease in a patient sample are provided. The methods of the invention comprise detecting overexpression of at least one biomarker in a body sample, wherein the biomarker is selectively overexpressed in high-grade cervical disease. In particular claims, the body sample is a cervical smear or monolayer of cervical cells. The biomarkers of the invention include genes and proteins that are involved in cell cycle regulation, signal transduction, and DNA replication and transcription. In particular claims, the biomarker is an S-phase gene. In some aspects of the invention, overexpression of a biomarker of interest is detected at the protein level using biomarker-specific antibodies or at the nucleic acid level using nucleic acid hybridization techniques. Kits for practicing the methods of the invention are further provided.