Carbostyril derivatives and serotonin reuptake inhibitors for treatment of mood disorders

Patent Number: 9387182

Patent Date: 2016-07-12

Patent type: utility

The pharmaceutical composition of the present invention comprises (1) a carbostyril derivative and (2) a serotonin reuptake inhibitor in a pharmaceutically acceptable carrier. The carbostyril derivative may be aripiprazole or a metabolite thereof, which is a dopamine-serotonin system stabilizer. The serotonin reuptake inhibitor may be fluoxetine, duloxetine, venlafaxine, milnacipran, citalopram, fluvoxamine, paroxetine, sertraline or escitalopram. The pharmaceutical composition of the present invention is useful for treating patients with mood disorders, particularly depression or major depressive disorder.

Inventors

First Name	Last Name	City	State	Country
Tetsuro	Kikuchi	-	-	-
Tsuyoshi	Hirose	-	-	-
Taro	Iwamoto	-	-	-

IPCs

Section	Class	Sub Class	Group	Sub Group
A	61	K	31	496
A	61	K	31	501
A	61	K	31	34
A	61	K	31	137
A	61	K	31	135
A	61	K	31	15
A	61	K	31	165
A	61	K	31	343
A	61	K	31	381
A	61	K	31	4525
A	61	K	31	138

Assignee

Organization	First Name	Last Name	City	State	Country
Otsuka Pharmaceutical Co., Ltd.	-	-	-	-	-